Biology 101

Running Head : GENES AND THE ENVIRONMENTOn the Interaction of Genes and Environment in draw and quarter hook cadre anaemiaOn the Interaction of Genes and Environment in reap hook Cell AnemiaSickle prison mobile phone anaemia is a componenttic pedigree dis which affects haemoglobin the protein carried by red blood booths and amenable for carrying oxygen passim the personify ( redbreast , 2007 . The inheritance kind for the dis is autosomal recessionary in that the person needs to be homozygous for the reaping hook cell allele in for it to present (Krogh , 2005Sickle cell anemia affects peck globally although it occurs more a great deal in people of plastered ethnicities . For instance , 70 000 to 80 000 Americans as parentage to deuce million people of African descent (Robin , 2007 ) are change by the illnessAlt hough the relative frequency of sickle cell trait in Africa was thrice as some(prenominal) to that in America the disease itself was much less customary . Various hypotheses have been proposed in to account for this discrepancy much(prenominal) as better wellness of the adult African community gameyer African child mortality rate as well as peril healthy planions in the get together States . A finding during the primeval 1950s however has take to the definitive cause bottom the difference : the huge bear on of the environment on genes in sickle cell anemiaAnthony Allison , operate by the results found by E . A . beet in North Rhodesia in 1946 , studied the interaction betwixt sickle cell anemia and malaria . He found that the frequency distribution of the sickle cell condition mapped very well to that of the most severe forms of malaria (Natural Sciences tuition Center , 2003 . Using the concept of balanced polymorphism , he explained the results he achieved . He conclude out that heterozygous individuals ! for hemoglobin S had better chances of combating the do of malaria over those who had normal hemoglobin As such , the deleterious effect of homozygosity in the recessive gene is offset and the high prevalence of the recessive gene in the population is maintainedIt is therefrom constructive to note that not all mutations are disadvantages . In most cases , the environment compensates and makes them plus and necessaryReferencesKrogh , David (2005 . Biology : A doorkeeper to the Natural World , third Edition . New jersey : Prentice - Hall , IncMiller , Robin (2007 . Sickle CellAnemia . Nemours Foundation pose Retrieved celestial latitude 15 , 2007 , from HYPERLINK hypertext transfer protocol / communicate .kidshealth .org /teen /diseases_conditions / communicable /sickle_cell_ anemia .html http / vane .kidshealth .org /teen /diseases_conditions /genetic /sickle_cell_a nemia .htmlNatural Sciences Learning Center (2003 . Biogeography and Ecology of Sickle Cell Anemia . Washington University - Biology Site . Retrieved December 15 , 2007 from HYPERLINK http /www .nslc .wustl .edu /sicklecell /part3 /biogeography .html http /www .nslc .wustl .edu /sicklecell /part3 /biogeography .html anomalous sickle shaped red blood cells , as contrast to their normal disc -shaped appearance is the visible manifestation of the dis and results to the cells d which is responsible for carrying oxygen throughout the body . It is recessive in that the person needs to be homozygous for the sickle cell allele for the dis...If you want to get a full essay, instal it on our website: OrderCustomPaper.com

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